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Antibodies sequestered in the liver granulomata of 8-week infections of CF1 mice bySchistosoma mansoni Sambon, 1907

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Summary

With out methods IgM, 7Sγ1 and C3 were detected in the egg-induced liveer granulomata of 8-week infections of CF1 mice bySchistosoma mansoni. It is speculated that, in addition to sequestration of antigens within these lesions by these antibodies, 7Sγ1 may be associated with the Hoeppli phenomenon, and IgM in combination with C3 may be responsible for the ultimate death of tmbryo or miracidium within the egg shell.

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References

  • Boros, D. L., Schwartz, H. J., Powell, A. E., Warren, K. S.: Delayed hypersensitivity, as manifested by granuloma formation, dermal reactivity, macrophage migration inhibition and lymphocyte transformation, induced and elicited in guinea pigs with soluble antigens ofSchistosoma mansoni eggs. J. Immunol.110, 1118–1125 (1973)

    CAS  Google Scholar 

  • Cheever, A. W., Kuntz, R. E., Myers, B. J., Moore, J. A., Huang, T. C.: Schistosomiasis hematobia in African Hamadryas and Gelada baboons. Amer. J. trop. Med. Hyg.23, 429–448 (1974)

    CAS  Google Scholar 

  • Cohen, S., Millstein, C.: Structure and biological properties of immunoglobulins. Advanc. Immunol.7, 1–89 (1962)

    Google Scholar 

  • Colley, D. G.: Immune responses to a soluble schistosomal egg antigen preparation during chronic primary infection withSchistosoma mansoni. J. Immunol.115, 150–156 (1975)

    PubMed  CAS  Google Scholar 

  • Hellström, I., Hellström, K. E., Evans, C. A.: Serum mediated protection of neoplastic cells from inhibition by lymphocytes immune to their tumor specific antigens. Proc. nat. Acad. Sci. (Wash.)62, 362–368 (1969)

    Article  Google Scholar 

  • Hoeppli, R.: Histological observations in experimentalSchistosomiasis japonica. Chin. med. J.46, 1179–1186 (1932)

    Google Scholar 

  • Lichtenberg, F., von: Studies on granuloma formation. III. Antigen sequestration and destruction in the schistosome pseudotubercle. Amer. J. Path.45, 75–93 (1964)

    Google Scholar 

  • Lichtenberg, F. von, Erickson, D. G., Sadun, E. H.: Comparative histopathology of schistosome granulomas in the hamster. Amer. J. Path.72, 149–168 (1973)

    Google Scholar 

  • Lichtenberg, F. von, Smith, J. H., Cheever, A.: The Hoeppli phenomenon in schistosomiasis. Comparative pathology and immunopathology. Amer. J. trop. Med. Hyg.15, 886–893 (1966).

    Google Scholar 

  • Moller, E., Moller, G.: Quantitative studies of the sensitivity of normal and neoplastic mouse cells to the cytotoxic action of isoantibodies. J. exp. Med.115, 527–533 (1962)

    Article  PubMed  CAS  Google Scholar 

  • Race, G. J., Michaels, R. M., Martin, J. H., Larsh, J. E., Matthews, J. L.:Schistosoma mansoni eggs: An electron microscopic study of shell pores and microbarbs. Proc. Soc. exp. Biol. (N. Y.)130, 990–991 (1969).

    CAS  Google Scholar 

  • Spiegelberg, H. L.: Biological activities of immunoglobulins of different classes and subclasses. Advanc. Immunol.19, 259–294 (1974)

    CAS  Google Scholar 

  • Winn, H. J.: Immune mechanisms in homotransplantation. I. The role of serum antibody and complement in the neutralization of lymphoma cells. J. Immunol.84, 530–538 (1960)

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, Baylor Medical Center, 75246, Dallas, Texas

    Franklin Sogandares-Bernal & Stephanie Brandt

  2. Department of Biology, Southern Methodist University, 75275, Dallas, Texas, USA

    Franklin Sogandares-Bernal & Stephanie Brandt

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  1. Franklin Sogandares-Bernal
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  2. Stephanie Brandt
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Sogandares-Bernal, F., Brandt, S. Antibodies sequestered in the liver granulomata of 8-week infections of CF1 mice bySchistosoma mansoni Sambon, 1907. Z. F. Parasitenkunde 50, 331–334 (1976). https://doi.org/10.1007/BF02462977

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  • DOI: https://doi.org/10.1007/BF02462977

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