Abstract
Putamen neuron spike activity associated with motor and nonmotor functions was studied in monkeys trained to behavioral programs consisting of a series of sequential actions. In general, each putamen neuron was activated during particular behavior fragments. The association of each individual neostriatal neuron with particular behavioral fragments was not constant. When the animal performed a different version of the same program (using different conditioned signals, right- or left-sided tasks, correct or erroneous performance). the neuron could lose its association with the animal's action and become involved in a different action to which it had previously produced no response. Thus, putamen neurons could demonstrate different functional modalities in different versions of the same actions. The use of additional versions of the given program always led to increases in the numbers of behavior fragments during which there were changes in the spike activity of the neurons of interest. This effect was significantly stronger in motor fragments of the program than in nonmotor fragments. These results show that putamen neurons do not have any defined specialization and have different functional modalities when the animal performs different versions of the same action. The nature of putamen neuron involvement in sensory-cognitive processes was more stable than in the organization of motor responses.
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References
S. V. Afanas'ev, B. F. Tolkunov, A. A. Orlov, and E. V. Selezneva, “Collective responses of neostriatal (putamen) neurons during alternative behavior in monkeys,” Fiziol. Zh. im. I. M. Sechenova,83, No. 1–2, 19–27 (1997).
A. A. Orlov, V. I. Shefer, and B. P. Mochenkov, “A miniature multichannel micromanipulator for independently moving microelectrodes in bundles,” Fiziol. Zh. SSSR,75, No. 9, 1275–1278 (1989).
B. F. Tolkunov, The Striatum and Sensory Specialization of the Neuronal Network [in Russian], Nauka, Leningrad (1978).
B. F. Tolkunov, “Organization of the specialized image of significant signals in the no network of the nonspecific brain structures,” in: Neuronal Plasticity and Memory Formation. International Brain Research Organization Monograph Series, No. 9, Raven Press, New York (1982), pp. 608–611.
B. F. Tolkunov, “Functional linking of the mechanisms of selecting significant signals and conditioned or motor responses,” Zh. Vyssh. Nerv. Deyat.,42, No. 5, 864–875 (1992).
B. F. Tolkunov, “The question of time and studies of the neuronal correlates of behavior,” Fiziol. Zh. im. I. M. Sechenova (1996) (in press).
B. F. Tolkunov and A. V. Golubev, “Evoked potentials in the rat neostriatum in conditions of local cooling of the cortex at the applied signal primary response zone,” Zh. Évolyuts. Biokhim. Fiziol.,24, No. 3, 350–356 (1988).
B. F. Tolkunov, A. A. Orlov, and S. V. Afanas'ev, “Models of the functions of the neostriatum and the activity of its neurons during behavior in monkeys,” Fiziol. Zh. im. I. M. Sechenova,81, No. 4, 12–20 (1995).
B. F. Tolkunov, A. A. Orlov, and S. V. Afanas'ev, “The activity of striatum neurons in the monkey brain during simultaneously performed actions,” Fiziol. Zh. im. I. M. Sechenova,81, No. 8, 121–128 (1995).
K. B. Shapovalova, “Possible mechanism of participation of the neostriatum in regulation of voluntary movement,” in: Soviet Scientific Reviews, Section F, T. M. Turpaev (ed.),6, No. 3, 3–85 (1993).
V. T. Shuvaev and V. I. Shefer, “The structure of neuronal activity in the caudate nucleus of the monkey during decision-taking and performance of different versions of a motor program consisting of a task with delayed spatial selection,” Fiziol. Zh. im. I. M. Sechenova,1, No. 1, 31–39 (1994).
T. Aosaki, M. Kimura, and A. M. Graybiel, “Temporal and spatial characteristics of tonically active neurons of the primate"s striatum,” J. Neurophysiol.,73, No. 3, 1234–1252 (1995).
J. W. Aldridge, R. J. Anderson, and J. T. Murphy, “Sensory-motor processing in the caudate nucleus and globus pallidum: a single-unit study in behaving primates,” Can. J. Physiol. Pharm.,58, 1192–1201 (1980).
J. B. Carman, W. M. Cowan, T. P. S. Powell, and K. E. Webster, “Bilateral cortico-striate projections,” J. Neurol. Neurosurg. Psychiat.,28, No. 1, 71–77 (1965).
M. D. Crutcher and G. E. Alexander, “Movement-related neuronal activity selectively coding either direction or muscle pattern in three motor areas of the monkey,” J. Neurophysiol.,64, No. 1, 151–163 (1990).
M. R. De Long and A. Georgopoulos, “Motor functions of basal ganglia,” in: Handbook of Physiology, J. M. Brookhart, M. B. Mountcastle, V. B. Brooks, and S. R. Geiger (eds.), Vol. 2 (1981), pp. 1017–1061.
T. W. Gardiner and P. J. Nelson, “Striatal neuronal activity during the initiation and execution of hand movements made in response to visual and vibratory cues,” Exp. Brain Res.,92, No. 1, 15–26 (1992).
P. S. Goldman-Rakic and L. D. Selemon, “Topography and corticostriatal projections in nonhuman primates and implications for functional parcellation of the neostriatum,” in: Cerebral Cortex Sensorimotor Areas and Aspects of Cortical Connectivity, Vol. 5, New York-London (1986), pp. 447–466.
O. Hikosaka, M. Sakamoto, and S. Usui, “Functional properties of monkey caudate neurons. I. Activities related to saccadic eye movements,” J. Neurophysiol.,61, No. 4, 780–798 (1989).
T. I. Lidsky and J. S. Schneider, “Effects of experience on striatal sensory responses,” Neurosci. Lett.,174, No. 2, 141–144 (1994).
H. Nishijo, S. Hattory, K. Makamoto, and T. Oho, “Basal ganglia and neural activity during operant feeding behavior in the monkey: relation to sensory integration and motor execution,” Brain Res. Bull.,27, No. 3/4, 463–468 (1991).
P. Pasik, T. Pasik, and M. Di Figlia, “The internal organization of the neostriatum in mammals,” in: The Neostriatum, Oxford (1979), pp. 5–36.
E. T. Rolls, “Responses of neurons in different regions of the striatum of the behaving monkey,” in: The Basal Ganglia: Structure and Function, J. S. McKenzie, et al. (eds.), New York (1984).
G. J. Royce, “Fluorescent double labeling studies of thalamocortical and corticostriatal neurons,” in: The Basal Ganglia: Structure and Function, J. S. McKenzie, R. E. Kemm, and L. N. Wilcock (eds.), New York (1984), pp. 131–146.
S. A. Snider and J. C. Lee, A Stereotaxic Atlas of the Monkey Brain (Macaca mulata), Chicago (1961).
R. P. Travis and D. L. Sparks, “Changes in unit activity during stimuli associated with food and shock reinforcement,” Physiol. Behav.,2, No. 1, 171–178 (1967).
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Laboratory for the Integrative Functions of the Brain, I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 44 M. Torez Prospekt, 194223 St. Petersburg, Russia. Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 83, No. 1–2, pp. 11–18, January–February, 1997.
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Tolkunov, B.F., Orlov, A.A., Afanas'ev, S.V. et al. Involvement of striatum (putamen) neurons in motor and nonmotor behavior fragments in monkeys. Neurosci Behav Physiol 28, 224–230 (1998). https://doi.org/10.1007/BF02462950
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DOI: https://doi.org/10.1007/BF02462950