Recovery of degenerate schizostatin production by screening single-basidiospore isolates inSchizophyllum commune
To recover degenerate schizostatin production in aSchizophyllum commune isolate, SANK 17785, we examined schizostatin production of 30 single-basidiospore isolates obtained from a basidiocarp of SANK 17785. One of the isolates showed high productivity (136–154 μg/ml) and maintained its high productivity for 26 mo. To explore other isolates with high schizostatin production, 76 single-basidiospore isolates from 7 wild basidiocarps were obtained and their schizostatin production was quantified. Four of the isolates produced more schizostatin than SANK 17785 did originally.
Key Wordsbasidiocarp formation genetic recombination Schizophyllum commune schizostatin single-basidiospore isolates
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