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Performance criteria for optimization of cardiac assistance

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Abstract

A performance criterion and weighting factors for the optimal cardiac assistance are investigated by applying Tellegen's network theorem and tolerance analysis on animal experimental data for left ventricular (LV) bypass on the failing heart. Two major factors with respect to cardiac assistance (total power delivered to the peripheral circulatory system, and changes in temporal pattern of ventricular contraction) are represented by two performance criteria,J 1 andJ 2 whereJ 1 relates to the sum of LV and pump power, andJ 2 relates to the “peakedness” factor of LV power. The total performance index (J) is determined as the weighted sum ofJ 1 andJ 2;J=w 1J1+w2J2. The weighting factors,w 1 andw 2, are computed as inverses of the tolerance in the performance contours with respect to improvement of stroke work per minute from pre- to post-bypass condition.

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Authors and Affiliations

  1. Department of Electrical Engineering, Rutgers University, 08854, Piscataway, NJ, U.S.A.

    B. G. Min

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  1. B. G. Min
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Min, B.G. Performance criteria for optimization of cardiac assistance. Bltn Mathcal Biology 41, 217–227 (1979). https://doi.org/10.1007/BF02460880

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