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Blood flow: Theory, effective viscosity and effects of particle distribution

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Abstract

A study is made of blood flow by assuming that the blood constitutes a suspension of cells in plasma instead of a simple homogeneous fluid. A macroscopic theory governing the motion of plasma in a plasma-cell system is derived from the local volume averaging method for a system without mass transfer between the phases, and its characteristic length is much larger than the size of the cells. The equations governing the motion of the local averaged fluid quantities include one additional term in the equation of motion and two additional terms in the energy equation. These terms represent, respectively, the force exerted upon the fluid by the particles, and the rate of heat transfer and work done upon the fluid by the particles. The theory is applied to obtain the effective viscosity as the explicit function of the volume concentration of the cells by assuming that the cells behave like rigid spherical particles with slip-collision, and the plasma is an incompressible Newtonian fluid. Comparison with existing experimental results shows a good agreement. The theory is also used to obtain the effects of cell distribution upon the overall effective viscosity in a circular tube. The quantitative result shows that there is a decrease in overall effective viscosity as the concentration of cells increases toward the center of the tube, and the overall effective viscosity is smaller than the flow with evenly distributed cells.

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Authors and Affiliations

  1. Department of Energy Engineering, University of Illinois at Chicago Circle, 60680, Chicago, IL

    Joseph C. F. Chow

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  1. Joseph C. F. Chow
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Chow, J.C.F. Blood flow: Theory, effective viscosity and effects of particle distribution. Bltn Mathcal Biology 37, 471–488 (1975). https://doi.org/10.1007/BF02459515

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  • DOI: https://doi.org/10.1007/BF02459515

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