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Structural changes in dog liver during adaptation to high altitude

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Vascular and tissue changes in the livers of dogs living on an altitude of 3200 m above sea level for various periods were studied by histological, morphometric, and electromicroscopic methods. Destructive changes were observed in hepatocytes after a month of exposure, which were due mainly to impaired hepatic microcirculation and increased from the center to the periphery of hepatic acinus. Ultrastructural changes occurred predominantly in the energy-producing and protein-synthesizing systems of hepatocytes.

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Authors and Affiliations

  1. Institute for Research on Physiology and Experimental Pathology at High Altitudes, Academy of Sciences, Bishkek, Kyrgyz Republic

    E. V. Orlova, M. V. Balykin & V. Kh. Gabitov

Authors
  1. E. V. Orlova
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  2. M. V. Balykin
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  3. V. Kh. Gabitov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 6, pp. 714–717, June, 1997

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Orlova, E.V., Balykin, M.V. & Gabitov, V.K. Structural changes in dog liver during adaptation to high altitude. Bull Exp Biol Med 123, 619–622 (1997). https://doi.org/10.1007/BF02458097

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  • DOI: https://doi.org/10.1007/BF02458097

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