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Specific binding of3H-melatonin to cell plasma membranes in rat thyroid gland

  • Experimental Biology
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Abstract

3H-melatonin binding sites were found in the cell membrane fraction from the thyroid gland of Wistar rats and their kinetic characteristics were determined. The number of receptors and dissociation constant depend on the duration of daytime, which probably determines rhythmic fluctuation of the sensitivity of thyrocytes to melatonin.

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Authors and Affiliations

  1. Ukrainian Institute of Pharmacotherapy and Endocrinological Diseases, Kharkov

    E. S. Rom-Boguslavskaya, V. S. Shcherbakova & I. V. Komarova

Authors
  1. E. S. Rom-Boguslavskaya
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  2. V. S. Shcherbakova
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  3. I. V. Komarova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 6, pp. 706–708, June, 1997

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Rom-Boguslavskaya, E.S., Shcherbakova, V.S. & Komarova, I.V. Specific binding of3H-melatonin to cell plasma membranes in rat thyroid gland. Bull Exp Biol Med 123, 612–614 (1997). https://doi.org/10.1007/BF02458095

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  • DOI: https://doi.org/10.1007/BF02458095

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