Skip to main content
Log in

Measurement of aortic compliance from the transthoracic admittance plethysmogram in the living dog

  • Published:
Medical and Biological Engineering and Computing Aims and scope Submit manuscript

Abstract

An attempt was made to measure the compliance and elastic modulus of the thoracic aorta from simultaneous recordings of the transthoracic admittance plethysmogram and intra-aortic pressure in living dogs. Initially, the compliance values determined by this method were correlated with those measured from the volume-pressure relationships in three different silicone-rubber tubes; these two groups of values were consistent with each other within the error range of ±10%. The mean value of the compliance of the thoracic aortae in four normal dogs (13–15 kg) measured by this method was 0·00387±0·00100 ml/mmHg cm. The elastic modulus E and velocity v of the pulse wave were calculated from this value; E=2·71±0·79×105 dN/m2 and v=4·52±2·44 m/s. These data were compared with those reported previously by other investigators. Taking simplicity, safety and practicability into consideration, it was concluded that this method would only be useful in clinics for the rough estimation of the elastic properties of the thoracic aorta.

Sommaire

Un essai a été entrepris pour mesurer le comportement et le coéfficient d'élasticité de l'aorte thoracique à partir d'enregistrements simultanés du pléthysmogramme d'admission transthoracique at de la pression intra-aortique dans des chiens vivants. Initialement, les valeurs de comportement déterminées par cette méthode furent associées à celles qui étaient mesurées à partir des rapports volume-pression dans trois tubes en caoutchouc de silicone différents. Ces deux groupes de valeurs étaient compatibles les unes avec les autres dans les limites de la gamme d'erreur de ± 10%. La valeur moyenne du comportement de l'aorte thoracique dans quatre chiens normaux (13–15 kg), relevée par cette méthode, était de 0,00387±0,00100 ml/mm Hg-cm. Le coéfficient d'élasticitéE et la vitesse de l'onde d'impulsion ν furent également déterminés à partir de cette même valuer, à savoir: E=2,71±0,79×106 dynes/cm2 et ν=4,52±2,44 m/s. Ces données furent ensuite comparées à celles qui avaient été précédemment formulées par d'autres enquêteurs. En tenant compte des facteurs de simplicité, sécurité et praticabilité, on en a conclu que cette méthode ne serait utile que dans les cliniques pour les évaluations approximatives des propriétés élastiques de l'aorte thoracique.

Zusammenfassung

Es wurde ein Versuch gemacht, die Übereinstimmung und das Elastizitätmodul der thorakalen Aorta durch gleichzeitiges Aufnehmen eines transthorakalen Admittanz-Plethysmogramms und Druck in der Aorta an lebenden Hunden zu messen. Anfänglish wurden die Übereinstimmungswerte, die durch dieses Verfahren bestimmt wurden, auf die mit Volumen-/ Druckverhältnis in drei verschiedenen Silikongummischläuchen gemessenen aufeinander in bezug gebracht. Diese beide Wertegruppen waren im Fehlerbereich von ±10% einheitlich. Der Mittelwert der Übereinstimmung der thorakalen Aorta bei vier normalen Hunden (13–15 kg), der mit diesem Verfahren gemessen wurde, betrug 0,00387±0,00100 ml/mm Hg/cm. Das ElastizitätsmodulE und die Geschwindigkeit der Impulswelle ν wurden von diesem Wert berechnet. E 3 2,71±0,79×106 Dyn/cm2 undv 3 4,52±2,44 m/s. Diese Daten wurden mit den schon früher von anderen Untersuchern vorgestellten verglichen. Unter Berücksichtigung von Einfachheit, Sicherheit und Durchführbarkeit wurde geschlossen, daß dieses Verfahren nur in der Klinik zur groben Schätzung der elastischen Eigenschaften der Thoraxaorta nützlich sein würde.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Arndt, J. O., Klauske, J. andMersch, F. (1968) The diameter of the intact carotid artery in man and its change with pulse pressure.Pflügers Archiv. 301, 230–240.

    Article  Google Scholar 

  • Arndt, J. O., Stegall, H. F. andWicke, H. J. (1971) Mechanics of the aortain vivo:Circulation Res:28, 693–704.

    Google Scholar 

  • Baker, L. E. (1971) Biological applications of electrical-impedance impedance measurements.In: IEE Medical Electronics Monographs 1–6, Hill, D. W. and Watson, B. W. (Eds.). Peter Peregrinus Ltd., 1–42.

  • Barnett, G. O., Mallos, A. J. andShapiro, A. (1961) Relationship of aortic pressure and diameter in the dog.J. Appl. Physiol. 16, 545–548.

    Google Scholar 

  • Bergel, D. H. (1961a) The elastic properties of the arterial wall.J. Physiol. 156, 445–457.

    Google Scholar 

  • Bergel, D. H. (1961b) The dynamic elastic properties of the arterial wall.156, 458–469.

    Google Scholar 

  • Cooley, W. L. (1972) The calculation of cardiac stroke volume from variations in transthoracic electrical impedance.Biomed. Eng. 7, 316–319.

    Google Scholar 

  • Gow, B. S. andTaylor, M. G. (1968) Measurement of viscoelastic properties of arteries in the living dog.Circulation Res. 23, 111–122.

    Google Scholar 

  • Ito, H., Yamakoshi, K. andTogawa, T. (1976a) Transthoracic admittance plethysmograph for measuring cardiac output.J. Appl. Physiol. 40, 451–454.

    Google Scholar 

  • Ito, H., Yamakoshi, K. andYamada, A. (1976b) Physiological and fluid-dynamic investigations of the transthoracic impedance plethysmography method for measuring cardiac output: Part II., Analysis of transthoracic impedance wave by perfusing dogs.Med. & Biol. Eng. 14, 373–378.

    Google Scholar 

  • Kinnen, E., Kubicek, W. G. andPatterson, R. P.: (1964) Thoracic cage impedance measurements. Impedance plethysmographic determination of cardiac output (a comparative study). Technical Documentary Report No. SAM-TDR-64-15, USAF School of Aerospace Medicine, Brooks Air Force Base, Texas, 1–8.

    Google Scholar 

  • Kinnen, E. (1970) Cardiac output from transthoracic impedance variations.Ann. NY Acad. Sci. 170, 747–756.

    Google Scholar 

  • Kubicek, W. G. Karnegis, J. N., Patterson, R. P., Witsoe, D. A. andMattson, R. H. (1966) Development and evaluation of an impedance cardiac output system.Aerospace Med. 37, 1208–1212.

    Google Scholar 

  • Kubicek, W. G., Patterson, R. P. andWitsoe, D. A. (1970) Impedance cardiography as a noninvasive method of monitoring cardiac function and other parameters of the cardiovascular system.Ann. NY Acad. Sci. 170, 724–732.

    Google Scholar 

  • Leitz, K. H. andArndt, J. O. (1968) Die Durchmesser-Druck-Beziehung des intakten Gefäßgebietes der A. carotis communis von Katzen.Pflügers Archiv 301, 50–69.

    Article  Google Scholar 

  • McDonald, D. A. (1968) Regional pulse-wave velocity in the arterial tree.J. Appl. Physiol. 25, 73–78.

    Google Scholar 

  • McDonald, D. A. (1974)Blood flow in arteries. 2nd Ed. Edward Arnold, 496.

  • Nyboer, J. (1947) Electrical impedance plethysmograph.In: Medical physics Vol. 1, byGlasser, O. (Ed.). The Year Book Publ., 340–341.

  • Patel, D. J., de Freitas, F. M., Greenfield, J. C. Jun. andFry, D. L. (1963) Relationship of radius to pressure along the aorta in living dogs.J. Appl, Physiol. 18, 1111–1117.

    Google Scholar 

  • Patel, D. J., Janicki, B. S. andCarew, T. E. (1969) Static anisotropic elastic properties of the aorta in living dog.Circulation Res. 25, 765–779.

    Google Scholar 

  • Patterson, R. T. (1965) Cardiac output determinations using impedance plethysmography. Thesis submitted to the Faculty of the Graduate School of the Unversity of Minnesota, Minneapolis, Minnesota, pp. 92.

  • Peterson, L. H., Jensen, R. E. andParnell, J. (1960) Mechanical properties of arteriesin vivo.Circulation Res. 8, 622–639.

    Google Scholar 

  • Peterson, L. H. (1962) Properties and behaviour of living vascular wall.Physiol. Rev. 42 (Suppl. 5), 309–325.

    Google Scholar 

  • Remington, J. W. andMimilton, W. F. (1945) The construction of a theoretical cardiac ejection curve from the contour of the aortic pressure pulse.Amer. J. Physiol. 144, 546–556.

    Google Scholar 

  • Woodcock, J. P. (1974) Plethysmography.Biomed. Eng. 9, 405–409, 417.

    Google Scholar 

  • Yamakoshi, K., Ito, H., Yamada, A., Tomino, T. andMiura, S. (1976) Physiological and fluid-dynamic investigations of the transthoracic impedance plethysmography method for measuring cardiac output: Part I, A fluid-dynamic approach to the theory using an expansible tube model.Med. & Biol. Eng. 14, 365–372.

    Google Scholar 

  • Yamakoshi, K., Togawa, T. andIto, H. (1977) Evaluation of the theory of cardiac output computation from transthoracic impedance plethysmogram.Med. & Boil. Eng. & Comput. 15.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ito, H., Yamakoshi, Ki., Shimazu, H. et al. Measurement of aortic compliance from the transthoracic admittance plethysmogram in the living dog. Med. Biol. Eng. Comput. 15, 618–626 (1977). https://doi.org/10.1007/BF02457919

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02457919

Keywords

Navigation