Summary
In this paper we describe some electrical- and ionic-permeability characteristics of liquid-lipid artificial membranes (model membranes made from millipore filters impregnated with phospholipids extracted from rat brain membranes), as well as the effect of monovalent cations, potassium and sodium, on the conductance of these membranes. Model membranes showed a sub-Nerstian cationic response to the cations, according to the series K+>Na+. Their conductance showed an almost exponential dependence on salt concentration and the current had Ohmic behaviour up to 180 mV, tending to saturation with voltage in higher range.
Riassunto
In questo lavoro si descrivono alcune caratteristiche di permeabilità elettrica e ionica di membrane artificiali di liquido-lipide (membrane modello fatte di filtri milliporici impregnati di fosfolipidi estratti da membrane di cervello di ratto), cosí come l'effetto di cationi monovalenti, potassio e sodio, sulla conduttanza di queste membrane. Le membrane modello mostrarono una risposta cationica subnernstiana ai cationi, secondo l'ordine K+>Na+. La loro conduttanza ha mostrato una dipendenza quasi esponenziale dalla concentrazione salina e la corrente ha avuto un comportamento ohmico fino a 180 mV, tendendo a saturazione con un voltaggio in un intervallo piú alto.
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Yova, D., Karnavezou, V. & Boudouris, G. Properties of ionic transport through liquid rat brain lipid artificial membranes. Il Nuovo Cimento D 4, 428–434 (1984). https://doi.org/10.1007/BF02450600
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DOI: https://doi.org/10.1007/BF02450600