Atypical coccidioidomycosis in an AIDS patient successfully treated with fluconazole

  • J. L. Hernández
  • S. Echevarría
  • A. García-Valtuille
  • F. Mazorra
  • R. Salesa


Cervical lymphadenopathy due toCoccidioides immitis occurred as the sole opportunistic infection in a Spanish patient with the acquired immunodeficiency syndrome. Twelve years earlier the patient had lived in the desert regions of the southwestern USA. After an initial course of high doses of fluconazole, the patient recovered without any sequelae. This is the first case of coccidioidomycosis in Spain.


Human Immunodeficiency Virus Fluconazole Multinucleated Giant Cell Coccidioidomycosis Cervical Lymphadenopathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Stevens DA: Coccidioidomycosis. New England Journal of Medicine 1995, 332: 1077–1082.PubMedCrossRefGoogle Scholar
  2. 2.
    Galgiani JN: Coccidioidomycosis: changes in clinical expression, serological diagnosis, and therapeutic options. Clinical Infectious Diseases 1992, 14, Supplement 1: 100–105.Google Scholar
  3. 3.
    Einstein HE, Johnson RH: Coccidioidomycosis: new aspects of epidemiology and therapy. Clinical Infectious Diseases 1993, 16: 349–354.PubMedGoogle Scholar
  4. 4.
    Smith MA, Anderson AE, Kostroff K: An unusual case of coccidioidomycosis. Journal of Clinical Microbiology 1994, 32: 1063–1064.PubMedGoogle Scholar
  5. 5.
    Bronnimann DA, Galgiani JN: Coccidioidomycosis. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8: 466–473.CrossRefGoogle Scholar
  6. 6.
    Ampel NM, Dols CL, Galgiani JN: Coccidioidomycosis during human immunodeficiency virus infection: results of a prospective study in a coccidioidal endemic area. American Journal of Medicine 1993, 94: 235–240.PubMedCrossRefGoogle Scholar
  7. 7.
    McNeil MM, Ampel NM: Opportunistic coccidioidomycosis in patients infected with human immunodeficiency virus: prevention issues and priorities. Clinical Infectious Diseases 1995, 21, Supplement 1: 111–113.Google Scholar
  8. 8.
    Galgiani JN, Ampel NM: Coccidioidomycosis in human immunodeficiency virus-infected patients. Journal of Infectious Diseases 1990, 162: 1165–1169.PubMedGoogle Scholar
  9. 9.
    Salkin D, Said A: Reinfection with coccidioidomycosis. Clinical Infectious Diseases 1993, 17: 1066.PubMedGoogle Scholar
  10. 10.
    Fish DG, Ampel NM, Galgiani JN, Dols CL, Kelly PC, Johnson CH, Pappagianis D, Edwards JE, Wasserman RB, Clark RJ, Antoniskis D, Larsen RA, Englender SJ, Petersen EA: Coccidioidomycosis during human immunodeficiency virus infection. A review of 77 patients. Medicine 1990, 69: 384–391.PubMedGoogle Scholar
  11. 11.
    Catanzaro A, Galgiani JN, Levine BE, Sharkey-Mathis PK, Fierer J, Stevens DA, Chapman SW, Cloud G and the NIAID Mycoses Study Group: Fluconazole in the treatment of chronic pulmonary and nonmeningeal disseminated coccidioidomycosis. American Journal of Medicine 1995, 98: 249–256.PubMedCrossRefGoogle Scholar

Copyright information

© MMV Medizin Verlag GmbH 1997

Authors and Affiliations

  • J. L. Hernández
    • 1
  • S. Echevarría
    • 1
  • A. García-Valtuille
    • 2
  • F. Mazorra
    • 2
  • R. Salesa
    • 3
  1. 1.Department of Internal Medicine, Hospital Marqués de ValdecillaUniversity of CantabriaSantanderSpain
  2. 2.Department of Pathology, Hospital Marqués de ValdecillaUniversity of CantabriaSantanderSpain
  3. 3.Department of Microbiology, Hospital Marqués de ValdecillaUniversity of CantabriaSantanderSpain

Personalised recommendations