International Journal of Anthropology

, Volume 10, Issue 4, pp 203–208 | Cite as

Complement C3 polymorphism in sixteen populations of Colombia. Results of “Expedicion humana”

  • J. E. Bernal
  • P. Sarmiento
  • I. Briceno
  • C. Duran
  • S. S. Papiha
Article
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Abstract

Blood samples of 1.022 individuals of both sexes, collected during the “Expedicion Humana” programme. Twelve Indian group, two Negroes, two urban and one mestizo populations of Colombia were C3 typed. The results showed the urban samples have C3*F genotype frequencies (17 and 20%) similar to the Spanish population. The Negroe system, with lower C3*F gene frequencies (3.5 and 7%) also resembled their parental populations in Africa. The Mestizo population reported in this study showed a lower value of the C3*F gene (2.2%) than previously studied. suggesting that the degree of admixture may vary in different regions of the country. As regards the Indian populations, there was a wide range of variation of the C3*F gene (0–19%) many tribes being monomorphic. This gene may be a marker of recent admixture in Amerindians, but there may be other genetic factors, such as selection and inbreeding in maintaining high levels of genetic polymorphism in tribes such as Guahibo.

Keywords

Complement polymorphism C3 Colombia Amerindians 

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Copyright information

© International Institute for the Study of Man 1995

Authors and Affiliations

  • J. E. Bernal
    • 1
  • P. Sarmiento
    • 1
  • I. Briceno
    • 2
  • C. Duran
    • 1
  • S. S. Papiha
    • 2
  1. 1.Institute of Human Genetics, the Medical SchoolUniversidad Javeriana BogotaColombia
  2. 2.Department of Human GeneticsUniversity of Newcastle upon TyneUK

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