Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 5, pp 1144–1146 | Cite as

Morphofunctional status of the ovaries in platidiam-treated rats

  • E. D. Gol'dberg
  • T. G. Borovskaya
  • T. I. Fomina
  • M. E. Smirnova
Morphology and Pathomorphology


Intravenous injection of the maximum tolerated dose of platidiam prolongs diestrus in rats. Degenerative changes develop in the ovaries containing fewer generative elements. These changes are reversible.

Key Words

rat estrous cycle ovary platidiam 


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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • E. D. Gol'dberg
    • 1
  • T. G. Borovskaya
    • 1
  • T. I. Fomina
    • 1
  • M. E. Smirnova
    • 1
  1. 1.Institute of Pharmacology, Research CenterSiberian Division of the Russian Academy of Medical SciencesTomsk

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