Abstract
The possibility of eliminating hyperproduction of antibodies to brain protein S-100 in immunized mice through specific immunocorrection by anti-idiotypic antibodies to this protein or their Fab fragments is explored. Anti-idiotypic antibodies and their Fab fragments inhibit humoral immune response to S-100, which correlates with normalization of several behavior responses.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 11, pp. 508–511, November, 1996
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Poletaev, A.B., Morozov, S.G. The use of anti-idiotypic antibodies for the correction of autoimmune reactions to brain protein S-100. Bull Exp Biol Med 122, 1091–1093 (1996). https://doi.org/10.1007/BF02447654
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DOI: https://doi.org/10.1007/BF02447654