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Effect of the garlic preparation alisat on the content of lipid peroxidation products, activity of some antioxidant enzymes, and blood lipoprotein level in patients with atherosclerosis

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

A 3-month therapy with Alisat (600 mg/day) results in a decrease in the plasma content of lipid peroxidation products (diene conjugates and malonic dialdehyde), activation of the antioxidant enzyme glutathione peroxidase in erythrocytes, increase in the high-density lipoprotein cholesterol, decrease in plasma cholesterol, and decrease in the low-density lipoprotein. This implies that Alisat has an antiatherogenic activity.

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References

  1. A. K. Zhuravlev, V. V. Murashko, and P. R. Kamchatov,Klin. Med.,66, No. 4, 35–37 (1988).

    CAS  Google Scholar 

  2. A. N. Klimov and N. G. Nikul'chiva,Lipids, Lipoproteins, and Atherosclerosis [in Russian], St. Petersburg (1995), pp. 155–175.

  3. V. Z. Lankin, A. F. Vikhert, A. K. Tikhadze, and T. I. Bondar',Vopr. Med. Khimii, No. 3, 18–24 (1989).

    Google Scholar 

  4. A. N. Orekhov and E. M. Pivovarova,Angiologiya Sosud. Khir., No. 1, 158–162 (1995).

    Google Scholar 

  5. V. V. Titov, E. D. Brener, and A. A. Zadoya,Lab. Delo, No. 1, 36–41 (1979).

    PubMed  Google Scholar 

  6. C. Beauchamp and J. Fridovish,Anal. Biochem.,44, No. 1, 276–287 (1971).

    Article  PubMed  CAS  Google Scholar 

  7. C. Cilady and A. Neil,J. R. Coll. Physicians Lond.,28, No. 1, 2–8 (1994).

    Google Scholar 

  8. E. Engual and P. Parmlan,Immunochemistry,8, 871–874 (1971).

    Article  Google Scholar 

  9. W. T. Friedewald, R. I. Levy, and D. S. Fredrickson,Clin. Chem.,18, 499–502 (1972).

    PubMed  CAS  Google Scholar 

  10. R. Gebhardt,Arzneimitteforschung Drug Res.,41, 800–804 (1991).

    CAS  Google Scholar 

  11. R. Gebhardt, Lipids,28, 613–619 (1993).

    PubMed  CAS  Google Scholar 

  12. J. Maral, K. Puget, and A. Michelson,J. Biol. Chem.,255, No. 3, 11108–11111 (1980).

    Google Scholar 

  13. S. Moncada, R. I. Glyglewski, and S. Bunting,Arteriosclerosis,2, 193–197 (1980).

    Google Scholar 

  14. A. N. Orekhov, V. V. Tertov, I. A. Sobenin, and E. M. Pivovarova,Ann. Med.,27, 63–65 (1995).

    PubMed  CAS  Google Scholar 

  15. D. E. Pagleo and W. N. Valentine,J. Lab. Clin. Med.,70, No. 1, 158–189 (1967).

    Google Scholar 

  16. S. Phelps and W. Harris,Lipids 28, 475–477 (1993).

    PubMed  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Second Department of Internal Diseases, Kursk State Medical University, USSR

    V. P. Mikhin & N. I. Gromnatskii

Authors
  1. V. P. Mikhin
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  2. N. I. Gromnatskii
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 11, pp. 502–504, November, 1996

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Mikhin, V.P., Gromnatskii, N.I. Effect of the garlic preparation alisat on the content of lipid peroxidation products, activity of some antioxidant enzymes, and blood lipoprotein level in patients with atherosclerosis. Bull Exp Biol Med 122, 1085–1087 (1996). https://doi.org/10.1007/BF02447652

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  • DOI: https://doi.org/10.1007/BF02447652

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