Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 5, pp 1082–1084 | Cite as

p-Aminobenzoic acid as a stimulator of angiogenesis

  • S. I. Akberova
  • A. A. Sologub
  • O. G. Stroeva
General Pathology and Pathological Physiology


p-Aminobenzoic acid (0.002 and 0.005% in a volume of 0.1 ml) stimulates angiogenesis in the yolk sac of chick embryos. It is more effective in a concentration of 0.005%, significantly increasing the length and branching of large vessels (by 27–33% and 35–43%, respectively) in comparison with the control (injection of 0.1 ml normal saline).

Key Words

p-aminobenzoic acid angiogenesis yolk sac chilck embryos 


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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • S. I. Akberova
    • 1
    • 2
  • A. A. Sologub
    • 1
    • 2
  • O. G. Stroeva
    • 1
    • 2
  1. 1.N. K. Kol'tsoy Institute of Developmental BiologyRussian Academy of SciencesMoscow
  2. 2.N. N. Narimanov Azerbaijan Medical UniversityBaku

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