Abstract
Experiments withCrepis capillaris dry seeds show that pretreatment with adrenaline hydrochloride and adrenaline hydrotartrate significantly reduces the number of aberrations induced by the supermutagen ethylmethane sulfonate. The effective concentration ranges for adrenaline adrenaline hydrotartrate and hydrochloride are 10−1–10−7 M and 10−3–10−7 M, respectively. Adrenaline hydrochloride is more effective than adrenaline hydrotartrate (79.1vs. 65%, respectively).
Similar content being viewed by others
References
M. D. Mashkovskii,Drugs [in Russian], Moscow (2985).
V. V. Roshchina,Acetylcholine and Biotransmitters in Plants [in Russian], Kazan' (1993).
V. V. Semenov, I. A. Studentsova, A. D. Durnev,et al., Vopr. Med. Khimii,40, No. 3, 48–51 (1994).
P. V. Sergeev and N. L. Shimanovskii,Receptors of Physiologically Active Substances [in Russian], Moscow (1987).
V. Yu. Urbakh,Biometrical Methods [in Russian], Moscow (1964).
M. F. El-Refai and J. H. Exton,Eur. J. Pharmacol.,62, 201–204 (1980).
J. H. Exton,Mol. Cell Endocrinol.,23, 233–264 (1981).
B. B. Hoffman and R. Lefkowitz,Annu. Rev. Pharmacol. Toxicol.,20, 581–608 (1980).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 10, pp. 427–429, October, 1998
Rights and permissions
About this article
Cite this article
Semenov, V.V., Ibragimova, M.Y. & Barabanshchikov, B.I. Modification of ethylmethane sulfonate-induced mytagenesis with adrenaline. Bull Exp Biol Med 126, 1023–1024 (1998). https://doi.org/10.1007/BF02447310
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02447310