Abstract
Methylprednisolone increased the content of laminine, cyclosporin increased the content of fibronectin, and cyclophosphamide suppressed the extracellular matrix production in experimental nephrotoxic nephritis and puromycin aminonucleoside nephrosis. Therapy should be chosen with due consideration of the extracellular matrix structure in different morphological variants of chronic glomerulonephritis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
S. J. Cameron,Kidney Int. Suppl.,50, No. 57, S119-S131 (1996).
D. E. Hricik, M. Chung-Park, and J. R. Sedor,N. Engl. J. Med., 339, 888–899 (1998).
R. O. Hynes,Cell,69, 11–25 (1992).
J. Martin, M. Davies, G. J. Thomas, and D. L. Lovett,Kidney Int.,36, 790–801 (1989).
F. B. Waldo, M. R. Benfield, and E. C. Kohaut,Pediatr. Nephrol.,6, 503–505 (1992).
M. Weber,Kidney Int.,41, 620–628 (1992).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 11, pp. 584–587, November, 1998
Rights and permissions
About this article
Cite this article
Krivoshchapov, L.G., Pal'tseva, E.M. Effects of immunosuppressors and cytostatics on the extracellular matrix production in experimental nephropathy. Bull Exp Biol Med 126, 1160–1163 (1998). https://doi.org/10.1007/BF02447263
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02447263