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Effect of sodium succinate on histomorphological changes of autodermic grafts in rats

  • Pharmacology and Toxicology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Sodium succinate was found to increase the viability of epithelial cells in autodermic transplants. It stimulated the proliferation of epidermal cells of the basal layer, enhanced the activity of succinate dehydrogenase, lactate dehydrogenase and adenosine triphosphatase, intensified the formation of keratin, and activated the ingrowth of blood vessels through the generation of functioning endothelial cells.

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Authors and Affiliations

  1. Department of Pharmacology, Department of Histology and Embriology, Kuban's State Medical Academy, Krasnodar, Russia

    P. A. Galenko-Yaroshevsky, G. M. Mogil'naya, A. F. Karas', K. S. Vas'kov, S. E. Gumenyuk & V. L. Popkov

  2. Laboratory of Biophysics, Institute of Otolaryngology, Ministry of Health, Kiev, Ukraine

    P. A. Galenko-Yaroshevsky, G. M. Mogil'naya, A. F. Karas', K. S. Vas'kov, S. E. Gumenyuk & V. L. Popkov

Authors
  1. P. A. Galenko-Yaroshevsky
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  2. G. M. Mogil'naya
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  3. A. F. Karas'
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  4. K. S. Vas'kov
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  5. S. E. Gumenyuk
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  6. V. L. Popkov
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Additional information

Translated fromByulleten' Experimental'noi Biologii i Meditsiny, Vol. 126, No. 11, pp. 555–560, November, 1998

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Galenko-Yaroshevsky, P.A., Mogil'naya, G.M., Karas', A.F. et al. Effect of sodium succinate on histomorphological changes of autodermic grafts in rats. Bull Exp Biol Med 126, 1135–1139 (1998). https://doi.org/10.1007/BF02447255

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  • DOI: https://doi.org/10.1007/BF02447255

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