Abstract
The indices of ethanol or water preference under conditions of free choice and the duration of ethanol-induced sleep were measured in rats from a heterogenous population before and after compulsory alcoholization. The development of alcohol motivation was shown to be accompanied by the impairment of orosensory recognition of the strength of tested alcohol solutions (5, 10, and 15%) and the appearance of significant positive correlations between the index of preference and the dose of alcohol consumed. The sensitivity to hypnotic effects of ethanol was found to be unstable.
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A. S. Batuev,Zh. Vysch. Nervn. Deyat.,42, No. 5, 836–842 (1992).
I. P. Lapin and L. G. Mutovkina,Farmakol. i Toksikol.,54, No. 3, 64–65 (1991).
Yu. M. Ostrovsky, V. I. Satanovskaya, S. Yu. Ostrovsky,et al., Metabolic Prerequisites and Consequences of Alcohol Consumption [in Russian], Minsk (1988).
P. F. Rokitsky,Biological Statistics [in Russian], Minsk (1973).
Yu. M. Ostrovsky, M. N. Sadovnik., V. I. Satanovskaya,et al., in:Animal Models of Alcohol Research, K. Erikssonet al. (Eds), New York (1980), pp. 463–465.
Yu. M. Ostrovsky, M. N. Sadovnik, V. I. Satanovskaya,et al., in:System Research in Physiology: Motivation in Functional Systems, A. Gordonet al. (Eds), New York-London (1987), Vol. 1, pp. 257–266.
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Translated fromByulleten' Experimental'noi Biologii i Meditsiny, Vol. 126, No. 11, pp. 534–537, November, 1998
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Satanovskaya, V.I., Bardina, L.R. Development of alcohol motivation in rats of a heterogenous population. Bull Exp Biol Med 126, 1117–1120 (1998). https://doi.org/10.1007/BF02447249
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DOI: https://doi.org/10.1007/BF02447249