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Effect of ionizing radiation on the expression of transforming growth factor-β

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Experiments demonstrate the stimulation of transforming growth factor-β expression in porcine skin soon after ψ-irradiation in a dose of 64 Gy and in mouse macrophages after whole body irradiation in a dose of 4 Gy, which suggests the involvement of macrophages that produce transforming growth factor-β during the early postirradiation period in the development of postirradiation fibrosis.

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References

  1. S. G. Zubova, A. O. Danilov, V. B. Okulov,et al., Vopr. Onkol.,42, No. 5, 80–85 (1996).

    PubMed  CAS  Google Scholar 

  2. R. K. Assoian, A. Komoriya, C. A. Meyers,et al., J. Biol. Chem.,258, No. 11, 7156–7160 (1983).

    Google Scholar 

  3. P. Gomezynski and N. Sacchi,Anal. Biochem.,162, 156–159 (1987).

    Google Scholar 

  4. R. J. Coffey, N. J. Sipes, C. C. Bascom,et al., Cancer Res.,48, 156–159 (1987).

    Google Scholar 

  5. J. L. Lefaix, F. Daburon, and G. Fayart,Health Phys.,63, 692–694 (1992).

    Article  PubMed  CAS  Google Scholar 

  6. J. N. Mansbridge and P. C. Hanawalt,J. Invest. Dermatol.,90, 336–341 (1988).

    Article  PubMed  CAS  Google Scholar 

  7. M. Martin, J. L. Lefaix, P. Pinton,et al., Radiat. Res.,134, 63–70 (1993).

    PubMed  CAS  Google Scholar 

  8. V. B. Okulov, O. V. Voytenkov, A. G. Ushmorov,et al., J. Cancer. Res. Clin. Oncol.,118, 537–541 (1992).

    Article  PubMed  CAS  Google Scholar 

  9. D. Rappolee, D. Mark, M. J. Banda, and Z. Werb,Science,241, 708–721 (1988).

    PubMed  CAS  Google Scholar 

  10. A. B. Roberts, M. V. Sporn, R. K. Assoian,et al., Proc. Nat. Acad. Sci. USA,83, 4167–4171 (1986).

    Article  PubMed  CAS  Google Scholar 

  11. S. M. Wahl,J. Clin. Immunol.,12, 61–74 (1992).

    Article  PubMed  CAS  Google Scholar 

Download references

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 11, pp. 529–533, November, 1998

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Zubova, S.G., Crechet, F., Gault, N. et al. Effect of ionizing radiation on the expression of transforming growth factor-β. Bull Exp Biol Med 126, 1113–1116 (1998). https://doi.org/10.1007/BF02447248

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  • DOI: https://doi.org/10.1007/BF02447248

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