Advertisement

Bulletin of Experimental Biology and Medicine

, Volume 121, Issue 6, pp 635–638 | Cite as

Virus-Induced morphological changes in arteries of rabbits with herpetic keratoconjunctivitisand of patients with generalized herpes infection

  • T. V. Amvros'eva
  • M. K. Nedz'ved'
  • V. I. Votyakov
  • O. T. Andreeva
Experimental Methods for Clinical Practice
  • 25 Downloads

Abstract

It is found that herpetic keratoconjunctivitis in rabbits and generalized herpes infection in humans is associated with virus-specific arterial damage. Experiments on rabbits show that virus-induced morphological changes in the aorta can be corrected with furavir. The role of herpes infection as a possible risk factor in atherogenesis is considered.

Key words

herpes infection arteries morphological changes 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    T. V. Amvros'eva, V. I. Votyakov, O. T. Andreeva,et al., Vopr. Virusol., No. 1, 61–64 (1992).Google Scholar
  2. 2.
    T. V. Amvros'eva, V. I. Votyakov, A. Yu. Chekina,et al., Ter. Arkh., No. 11, 48–50 (1994).Google Scholar
  3. 3.
    A. G. Kolomietset al. (Eds.),Generalized Herpes Infection: Facts and Concepts [in Russian], Minsk (1992).Google Scholar
  4. 4.
    R. A. Kupchinskii, L. I. Matskin, T. N. Azarovskaya,et al., Vopr. Virusol., No. 4, 479–481 (1988).Google Scholar
  5. 5.
    E. P. Benditt, T. Barrett, J. K. McDougall,Proc. Natl. Acad. Sci. USA,80, 6386–6389 (1983).PubMedCrossRefGoogle Scholar
  6. 6.
    R. S. Cottrell,Lancet,1, 520–524 (1984)CrossRefGoogle Scholar
  7. 7.
    C. G. Fabricant, J. Fabricant, M. M. Litrenta,et al., J. Exp. Med.,148, 335–340 (1978).PubMedCrossRefGoogle Scholar
  8. 8.
    C. G. Fabricant, D. P. Hajjar, C. R. Minick,et al., Fed. Proc.,39, 1110–1118 (1980).Google Scholar
  9. 9.
    F. Gyorkey, J. L. Melnick, G. A. Guinn,et al., Exp. Mol. Pathol.,40, 328–329 (1984).PubMedCrossRefGoogle Scholar
  10. 10.
    D. P. Hajjar,Am. J. Pathol.,139, 1195–1211 (1991).PubMedGoogle Scholar
  11. 11.
    D. P. Hajjar, C. G. Fabricant, C. R. Minick,et al., Am. J. Pathol.,122, 62–70 (1986).PubMedGoogle Scholar
  12. 12.
    D. P. Hajjar, K. B. Pomerantz, D. J. Falcone,et al., J. Clin. Invest.,80, 1317–1321 (1987).PubMedCrossRefGoogle Scholar
  13. 13.
    W. B. Kannell,Med. Clin. North Am.,58, 363–369 (1974).Google Scholar
  14. 14.
    J. L. Melnick, E. Adam, and M. E. DeBakey,J. Am. Med. Assoc.,263, 2204–2207 (1990).CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • T. V. Amvros'eva
    • 1
  • M. K. Nedz'ved'
    • 1
  • V. I. Votyakov
    • 1
  • O. T. Andreeva
    • 1
  1. 1.Department of Viral Activity InhibitorsBelarus Institute of Epidemiology and MicrobiologyMinsk

Personalised recommendations