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Pathogenesis of fetal hypertrophic cardiomyopathy in insulin-dependent diabetes mellitus

  • Experimental Methods for Clinical Practice
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Abstract

The development of fetuses and their hearts (24th–37th week of pregnancy) in mothers with insulin-dependent diabetes mellitus of various severity was studied by M-echocardiography, dopplerometry, and fetometry. A relationship is demonstrated between the early formation of macrosomia and cardiomyopathy, on the one hand, and the severity of diabetes, on the other. Along with metabolic disorders, hemodynamic disturbances in the mother-placenta-fetus system, which depend on the disease severity, play a role in the pathogenesis of fetal cardiomyopathy.

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Authors and Affiliations

  1. Laboratory of Fetal Physiology and Pathophysiology, D. O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg

    M. F. Litvinova

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  1. M. F. Litvinova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 6, pp. 698–701, June, 1996

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Litvinova, M.F. Pathogenesis of fetal hypertrophic cardiomyopathy in insulin-dependent diabetes mellitus. Bull Exp Biol Med 121, 632–634 (1996). https://doi.org/10.1007/BF02447138

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  • DOI: https://doi.org/10.1007/BF02447138

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