The effect of various incorporated doses of131I on immunological reactions of the organism
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Administration of radioisotope131I at 148 kBq/g body weight results in an inhibition of the primary immune response and in a decrease of proliferating activity of mouse lymphocytes in response to alloantigen stimulation. The number of antibody-producing spleen cells for immunization of mice with sheep erythrocytes diminished after administration of131I at 74 kBq/g animal weight.
Key Wordslymphocyte immunity immune system 131I
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- 2.I. Ya. Vasilenko, in:Kinetics of Metabolism and Biological Action of Radioactive Iodine Isotopes [in Russian], Moscow (1989), pp. 29–41.Google Scholar
- 3.Yu. I. Moskalev,Ibid., pp. 7–28.Google Scholar
- 4.D. G. Rokhlin and V. P. Zadvornova,Ionizing Radiation in the Diagnosis and Treatment of Thyroid Cancer [in Russian], Leningrad (1972).Google Scholar
- 5.V. V. Khorobrykh, L. V. Pronin, A. F. Kirkin, and A. V. Sanin,Immunologiya, No. 3, 76–79 (1983).Google Scholar
- 6.N. K. Jerne and A. A. Nordin,Science,140, 405–407 (1963).Google Scholar