Bulletin of Experimental Biology and Medicine

, Volume 121, Issue 6, pp 599–601 | Cite as

The effect of various incorporated doses of131I on immunological reactions of the organism

  • A. S. Solov'ev
  • N. V. Gurova
  • N. E. Shchebnikova
Microbiology and Immunology


Administration of radioisotope131I at 148 kBq/g body weight results in an inhibition of the primary immune response and in a decrease of proliferating activity of mouse lymphocytes in response to alloantigen stimulation. The number of antibody-producing spleen cells for immunization of mice with sheep erythrocytes diminished after administration of131I at 74 kBq/g animal weight.

Key Words

lymphocyte immunity immune system 131I 


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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • A. S. Solov'ev
    • 1
  • N. V. Gurova
    • 1
  • N. E. Shchebnikova
    • 1
  1. 1.Department of Medical BiologySmolensk Medical AcademySmolenskUSSR

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