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Alterations of cortical neurons and their dendrites after chronic alcohol intoxication

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Alterations occurring in the neurons of rat sensorimotor cortex 1, 2, and 4 months after a 4-month alcohol intoxication and 1 and 4 months after a 1-year alcoholization are studied by the methods of Nissl and Golgi. Pronounced dystrophic changes in cortical neurons and dendrites as well as reparative processes in the cell body are revealed 1 month after a 4-month intoxication. The recovery period for the upper cortical layer neurons (phylogenetically younger) is faster than that of neurons from the lower layers (phylogenetically older), as well as that of hypochromatousvs. hyperchromatous cells. Normalization of dendrite structure is slower than that of the cell body. Four months after a 1-year alcohol intoxication the structure of cortical neurons and dendrites is not restored.

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Authors and Affiliations

  1. Laboratory of Brain Ultrastructure, Institute of Brain Research, Russian Academy of Medical Sciences, Moscow

    E. N. Popova

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  1. E. N. Popova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 10, pp. 467–470, October, 1996

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Popova, E.N. Alterations of cortical neurons and their dendrites after chronic alcohol intoxication. Bull Exp Biol Med 122, 1056–1058 (1996). https://doi.org/10.1007/BF02447036

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  • DOI: https://doi.org/10.1007/BF02447036

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