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Investigation of transcription in nerve cells and hepatocytes of WAG and F344 rats of different ages

  • Experimental Biology
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Abstract

The effects of morphine and the protease inhibitor antipain on the RNA synthesis in nerve cells and hepatocytes are studied in rats of two inbred strains (WAG and F344) differing in narcologic resistance and age. The effects of morphine and antipain on the intensity of RNA synthesis are assessed by incorporation of3H-uridine into the neurons of sensorimotor cortex, hypothalamic ventromediial nucleus, blue spot, superior, and superficial cervical ganglion and in hepatocytes. These agents produce different effects on transcription in WAG and F344 rats.

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Authors and Affiliations

  1. Department of Biology, Russian State Medical University, Moscow

    V. N. Yarygin, E. V. Lipkina & A. G. Mustafin

Authors
  1. V. N. Yarygin
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  2. E. V. Lipkina
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  3. A. G. Mustafin
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 10, pp. 427–431, October, 1996

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Yarygin, V.N., Lipkina, E.V. & Mustafin, A.G. Investigation of transcription in nerve cells and hepatocytes of WAG and F344 rats of different ages. Bull Exp Biol Med 122, 1023–1027 (1996). https://doi.org/10.1007/BF02447026

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  • DOI: https://doi.org/10.1007/BF02447026

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