Abstract
The rate of spontaneous restoration of the volume of circulating plasma after blood loss (2% of body weight) is different in anesthetized newborn piglets and adult cats. The ability to restore circulating plasma volume is lost within the first weeks after birth, correlating with the interstitial glycosaminoglycan content. Newborn piglets (1–21-day-old) restore circulating plasma volume within several hours after blood loss, their aortic glycosaminoglycan content being almost two-fold lower than that in 22–30-day-old piglets that cannot rapidly restore the circulating plasma volume. The role of the interstitial gel in the replacement of circulating plasma volume is discussed.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 10, pp. 391–394, October, 1996
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Dzhurko, B.I., Krylov, M.K., Assur, M.V. et al. Restoration of circulating plasma volume after blood loss in newborn and adult mammals: a comparative analysis. Bull Exp Biol Med 122, 991–993 (1996). https://doi.org/10.1007/BF02447016
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DOI: https://doi.org/10.1007/BF02447016