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Bulletin of Experimental Biology and Medicine

, Volume 126, Issue 2, pp 787–789 | Cite as

Disorders in early embryonal cellular proliferative properties distort the postnatal formation of nervous, immune, and endocrine regulation systems in a newborn

  • I. V. Filyushkin
  • A. N. Ignatov
Biophysics and Biochemistry
  • 20 Downloads

Abstract

Disorders in the postnatal nervous, immune, and endocrine regulation systems were revealed in the progeny of rats irradiated during the preimplantation period of embryogenesis. These disorders persist till adult age. The direction of disorders confirms the hypothesis about memorization of changed proliferative properties of embryonal cells during the development of the (pro)endocrine system of a new organism. Memorization results in distortion of postnatal nervous immunoendocrine regulation: hypertrophy of the endocrine component and coadaptive underdevelopment of the nervous and immune components.

Key Words

embryogenesis early embryo nervous regulation immune regulation endocrine regulation 

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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • I. V. Filyushkin
    • 1
  • A. N. Ignatov
    • 1
  1. 1.State Research CenterInstitute of Biophysics, Ministry of Health of RussiaMoscow

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