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Effect of histidine-containing dipeptides on brain tyrosine hydroxylase

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Histidine-containing dipeptides inhibit highly purified tyrosine hydroxylase. The degree of inhibition is dependent on the peptide structure and decreases according to the following sequence: carnosine>anserine>homocarnosine. This effect is not associated with the buffer and antioxidant properties of the dipeptide.

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References

  1. A. A. Boldyrev,Biokhimiya,57, 1302–1310 (1992).

    CAS  Google Scholar 

  2. A. V. Val'dman, M. M. Kozlovskaya, I. P. Ashmarin,et al., Byull. Eksp. Biol. Med.,92, No. 7, 31–33 (1981).

    Google Scholar 

  3. M. F. Mineeva,Vopr. Med. Khim., No. 2, 274–279 (1976).

    Google Scholar 

  4. M. F. Mineeva, V. S. Kudrin, E. A. Kuznetsova,et al., Khim.- Farm. Zh.,11, No. 9, 66–72 (1979).

    Google Scholar 

  5. S. E. Severin,Biokhimiya,57, 1285–1295 (1992).

    CAS  Google Scholar 

  6. V. P. Skulachev, —Ibid.,,57, 1311–1316.

    CAS  Google Scholar 

  7. S. Biffo, R. DeLucia, B. Mulatero,et al., Brain Res.,528, 353–357 (1990).

    Article  PubMed  CAS  Google Scholar 

  8. A. Boldyrev and S. Severin,Adv. Enzyme Regul.,30, 175–193 (1990).

    Article  PubMed  CAS  Google Scholar 

  9. M. Levitt, S. Spector, A. Sjoerdsma and S. Udenfriend,J. Pharmacol. Exp. Ther.,148, 1–8 (1965).

    PubMed  CAS  Google Scholar 

  10. M. F. Mineyeva, V. S. Kudrin, and A. Yu. Shemanov, in:Drug Dependence and Emotional Behavior (ed. A. V. Valdman), Plenum Press, New York-London (1986), pp. 303–325.

    Google Scholar 

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 4, pp. 420–422, April, 1996

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Mineeva, M.F., Stvolinskii, S.L. Effect of histidine-containing dipeptides on brain tyrosine hydroxylase. Bull Exp Biol Med 121, 382–384 (1996). https://doi.org/10.1007/BF02446734

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  • DOI: https://doi.org/10.1007/BF02446734

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