Bulletin of Experimental Biology and Medicine

, Volume 121, Issue 4, pp 374–377 | Cite as

Peculiarities of the effect of parathyroid hormone on the relaxation of rat myocardium

  • T. A. Barabanova
  • S. K. Churina
Biophysics and Biochemistry


Contraction of rat myocardium is recorded in a regime of physiological loading that simulates the function of the intact myocardium. Addition of parathyroid hormone accelerates relaxation of the rat myocardium in the control solution and in a solution containing norepinephrine or high calcium concentrations. In a regime of isometric loading the addition of parathyroid hormone inhibits relaxation. At a low Ca concentration in the medium, parathyroid hormone has no effect on the rate of relaxation.

Key Words

myocardium relaxation parathyroid hormone 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    V. V. Barabanova,Fiziol. Zh. SSSR,63, No. 9, 1312–1317 (1977).PubMedGoogle Scholar
  2. 2.
    F. A. Blyakhman, V. Ya. Izakov, and A. D. Mikh, —Ibid.,,70, No. 11, 1581–1583 (1984).Google Scholar
  3. 3.
    D. Chemla, J. Lecarpentier, J. L. Martin,et al., Am. J. Physiol.,250, No. 2-3, H1009-H1016 (1986).Google Scholar
  4. 4.
    G. Raisz,Triangle,22, No. 2-3, 81–90 (1983).Google Scholar
  5. 5.
    R. G. Russel,Adv. Pharmacol. Chemother.,3, 3–14 (1979).Google Scholar

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • T. A. Barabanova
    • 1
  • S. K. Churina
    • 1
  1. 1.Laboratory of Experimental and Clinical Cardiology, I. P. Pavlov Institute of PhysiologyRussian Acadamy of SciencesSt. Petersburg

Personalised recommendations