Abstract
Considerable regional differences in the phospholipid composition of mitochondrial membranes are found in the brain of cats in the terminal phase of hemorrhagic shock. The most prominent alteration is noted in the medulla oblongata and consists in a progressive elimination of phosphatidylcholine. Changes in the main phospholipids in mitochondrial membranes of the cerebral hemispheres are less pronounced and consist in a drop of phosphatidylinositol and phosphatidylethanolamine. Accumulation of lysophosphatidylcholine and lysophosphatidylethanolamine is a regular feature of the studied mitochondria. Accumulation of lysophosphatidylserine is found primarily in mitochondrial membranes of the medulla oblongata.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 4, pp. 387–391, April, 1996
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Kryzhanovskii, G.N., Leskova, G.F. & Udovichenko, V.I. Changes in phospholipid composition of mitochondria in the medulla oblongata and frontal lobes of the cerebral hemispheres in hemorrhagic shock in cats. Bull Exp Biol Med 121, 352–355 (1996). https://doi.org/10.1007/BF02446725
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DOI: https://doi.org/10.1007/BF02446725