Abstract
Benzodiazepine tranquilizers, phenazepam and flunitrazepam, administered to random-bred albino male rats in superlow doses (10−9–10−15 mol/kg), are shown to exert an anxiolytic effect in the conflict test. In contrast to the case with the usual doses, the above effect is not accompanied by marked myorelaxant or sedative effects.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, № 2, pp. 164–166, February, 1996
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Molodavkin, G.M., Burlakova, E.B., Chernyavskaya, L.I. et al. Pharmacological analysis of the activity of phenazepam and flunitrazepam administered in superlow doses. Bull Exp Biol Med 121, 151–153 (1996). https://doi.org/10.1007/BF02446622
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DOI: https://doi.org/10.1007/BF02446622