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Effect of ozone on lipid peroxidation in rat hearts isolated against the background of clinical death

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Clinical death of outbred albino rats ensues after rapid blood loss due to a cut in the coronary coronary artery. Five minutes later, the isolated heart is perfused with ozonized Krebs-Henseleit solution. The activity of the antioxidant system in the heart is increased compared with that during routine oxygenation. The intensity of lipid peroxidation assessed by the intensity of chemiluminescence and the amount of lipid peroxidation products is significantly decreased during ozonization.

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Authors and Affiliations

  1. Central Research Laboratory, Nizhnii Novgorod Medical Academy, Nizhnii Novgorood, USSR

    K. N. Kontorshchikova & T. I. Solov'eva

Authors
  1. K. N. Kontorshchikova
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  2. T. I. Solov'eva
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, № 2, pp. 161–163, February, 1996

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Kontorshchikova, K.N., Solov'eva, T.I. Effect of ozone on lipid peroxidation in rat hearts isolated against the background of clinical death. Bull Exp Biol Med 121, 148–150 (1996). https://doi.org/10.1007/BF02446621

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  • DOI: https://doi.org/10.1007/BF02446621

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