Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 3, pp 887–889 | Cite as

State of the myocardium in rats of a new hypertensive strain

  • M. D. Shmerling
  • A. R. Antonov
  • I. M. Korostyshevskaya
  • A. L. Markel'
  • V. F. Maksimov
  • E. E. Filyushina
  • G. S. Yakobson
General Pathology and Pathological Physiology
  • 18 Downloads

Abstract

Study of the heart in a new strain of rats with hereditary stress-induced hypertension (NISAG) reveals a complex of structural and functional changes which are analogous to the manifestations of essential hypertension. These changes are shown to be adaptive-compensatory in nature and indicative of limited functional reserves of the hypertrophic myocardium.

Key Words

arterial hypertension stress myocardium hormones electrolytes 

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • M. D. Shmerling
    • 1
    • 2
    • 3
  • A. R. Antonov
    • 1
    • 2
    • 3
  • I. M. Korostyshevskaya
    • 1
    • 2
    • 3
  • A. L. Markel'
    • 1
    • 2
    • 3
  • V. F. Maksimov
    • 1
    • 2
    • 3
  • E. E. Filyushina
    • 1
    • 2
    • 3
  • G. S. Yakobson
    • 1
    • 2
    • 3
  1. 1.Institute of PhysiologySiberian Division of the Russian Academy of Medical SciencesNovosibirsk
  2. 2.Institute of Cytology and GeneticsSiberian Division of the Russian Academy of SciencesNovosibirsk
  3. 3.Novosibirsk Medical InstituteNovosibirsk

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