Lipid peroxidation in the brain of rats differing in resistance to emotional stress
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It is found for each of the rat brain regions studied (cerebral cortex, subjacent white substance, and brainstem) that both the initial levels of 2-thiobarbituric acid-reactive products and the rates of their increment are highest in rats resistant to emotional stress and lowest in stress-prone rats, and that the rates at which lipid peroxidation products accumulate are highest in the brainstem and lowest in the white substance. A correlation is presumed to exist between individual resistance to cerebral ischemia and the rate of lipid peroxidation in particular brain regions of healthy rats.
Key wordslipid peroxidation rat brain open-field behavior
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- 1.I. V. Gannushkina, A. L. Antelava and M. V. Baranchikova,Bull. Eksp. Biol. Med.,118, № 10, 360–363 (1994).Google Scholar
- 3.E. V. Gubler and A. A. Genkin,Use of Nonparametric Statistical Tests in Biomedical Research [in Russian], Leningrad (1973).Google Scholar
- 4.A. L. Markel' and R. A. Khusainov,Zh. Vyssh. Nervn. Deyat., № 6, 1314 (1976).Google Scholar
- 5.Yu. G. Skotselyas, E. A. Yumatov, and E. M. Krokhina, in:Models and Methods for the Study of Various Types of Experimental Emotional Stress. Proc. All-Union Symposium [in Russian], Volgograd (1977), p. 175.Google Scholar
- 6.K. V. Sudakov,Pat. Fiziol., №, 1, 3 (1989).Google Scholar
- 7.K. V. Sudakov, T. I. Belova, and E. A. Yumatov, in:Arterial. Hypertension, Proc. Soviet-American Symposium [in Russian], Moscow (1980), p. 170.Google Scholar
- 8.K. V. Sudakov, E. A. Yumatov, and L. S. Ul'yaninskii,Fiziol. Zh. SSSR,74, № 11, 1535 (1988).Google Scholar
- 10.H. I. Kohn and et al.,J. Pharmacol.,82 № 2, 292 (1944).Google Scholar