Recovery of colony-forming capacity of murine stem hemopoietic and blood cells under the effect of 1-β-D-arabinofuranosyl cytosine
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The cytostatic 1-β-D-arabinofuranosyl cytosine (cytarabine) in a dose of 200 mg/kg decreases blood count of nuclear cells in mice, to 60% and inhibits colony formation in the spleen for 8 days. The Resist repair system developed by us normalizes the total count within 3 days after cytarabine injection and repairs colony-forming activity of stem hemopoietic cells within 5 days, if Resist is injected after the, cytostatic, and within 8 days, if it is injected before cytarabine. Thus, Resist restores, immunity and hemopoiesis systems in cancer patients treated by radio- and chemotherapy.
Key Words1-β-D-arabinofuranosyl cytosine stem hemopoietic cell blood cells Resist
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