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Effect of the synthetic antiheparin agent quaternary ammonium salt of oligomer 25-conidine on liver regeneration

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Single injection of quaternary ammonium salt of oligomer-25 conidine to rats with acute CCI4-induced hepatitis promotes normalization of morphological and biochemical markers of hepatic injury in comparison with untreated animals. On day 3 postinjection the number of mitosis increased 2–3-fold.

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Authors and Affiliations

  1. I. M. Sechenov Moscow Medical Academy, Moscow

    V. A. Golencheko, s. A. Silaeva, A. B. Shekhter, A. V. Gavril'chak & A. Ya. Nikolaev

  2. Russian State Medical University, Moscow

    V. S. Efimov

Authors
  1. V. A. Golencheko
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  2. s. A. Silaeva
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  3. A. B. Shekhter
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  4. A. V. Gavril'chak
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  5. A. Ya. Nikolaev
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  6. V. S. Efimov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 7, pp. 56–60, July, 1998

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Golencheko, V.A., Silaeva, s.A., Shekhter, A.B. et al. Effect of the synthetic antiheparin agent quaternary ammonium salt of oligomer 25-conidine on liver regeneration. Bull Exp Biol Med 126, 690–693 (1998). https://doi.org/10.1007/BF02446062

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  • DOI: https://doi.org/10.1007/BF02446062

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