Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 1, pp 717–719 | Cite as

Typifying presynaptic M-cholinergic receptors in different structures of rat brain

  • N. P. Podosinovikova
  • L. F. Gorobets
  • V. B. Dolgo-Saburov
Experimental Biology

Abstract

Pre- and postsynaptic M-cholinergic receptors are typified by radioligand analysis with selective cholinoblockers by comparing ligand binding in homogeneous and synaptosomal fractions of different structures of rat brain. It is found that presynaptic receptors of the hemispheres belong to M3 subtype and those of the brain stem are probably of M4 subtype.

Key Words

presynapsis muscarinic cholinergic receptors heterogeneity 

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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • N. P. Podosinovikova
    • 1
  • L. F. Gorobets
    • 1
  • V. B. Dolgo-Saburov
    • 1
  1. 1.Institute of ToxicologyMinistry of Health of RussiaSt. Petersburg

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