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Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 1, pp 687–688 | Cite as

Cardiomodulating actions of low-molecular peptides from various groups

  • A. T. Grechko
  • V. N. Kalikhevich
  • Z. A. Ardemasova
  • S. I. Churkina
Biochemistry and Biophysics
  • 17 Downloads

Abstract

A total of 61 low-molecular peptides belonging to various groups was tested and compared for their cardiomodulating potentials usingin situ isolated frog hearts, and some neuropeptides among them showed marked cardiomodulating activity, as was evidenced by the substantial alterations they caused in the recorded parameters of strophanthin K cardiotoxicity.

Key Words

heart strophanthin K peptides functional modulation 

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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • A. T. Grechko
    • 1
    • 2
  • V. N. Kalikhevich
    • 1
    • 2
  • Z. A. Ardemasova
    • 1
    • 2
  • S. I. Churkina
    • 1
    • 2
  1. 1.Laboratory for Research on the Physiology of Extremal StatesAcademy of Military MedicineSt. Petersburg
  2. 2.Chemical Research InstituteState UniversitySt. Petersburg

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