Abstract
The ability of estradiol, progesterone, and chorionic gonadotropin to influence prostaglandin F2α production by intact splenocytes of CBA mice was studied. Estradiol and progesterone similarly activated the processes of prostaglandin F2α production. No relationship was revealed between the effect and the concentration of the hormones. Chorionic gonadotropin activated prostaglandin production by immunocompetent cells but only when used in a concentration reflecting the peak of its physiological secretion. Combining gonadotropin with estradiol or progesterone did not lead to any appreciable differences in the prostaglandin-stimulating action of each hormone alone.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 8, pp. 178–180, August, 1995
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Shirshev, S.V., Shilov, Y.I. & Kevorkov, N.N. Contribution of the reproductive hormones to the regulation of prostaglandin F2α production by immunocompetent cells. Bull Exp Biol Med 120, 823–825 (1995). https://doi.org/10.1007/BF02445964
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DOI: https://doi.org/10.1007/BF02445964