Bulletin of Experimental Biology and Medicine

, Volume 120, Issue 2, pp 809–811 | Cite as

Variation in antiinfectious nonspecific resistance of the organism caused by cholinergic stimulation

  • P. F. Zabrodskii
Pharmacology and Toxicology


Cholinergic stimulation (acetylcholine, aceclidine, armin) is found to improve antiinfectious nonspecific resistance in mice. The effect depends on the dose of cholinomimetic (armin), is maximal during the first 18 hours of the infectious process, and is determined by serum antibacterial activity, lysozyme activity, and the function of neutrophils and natural killers.

Key Words

cholinergic stimulation antiinfectious resistance nonspecific factors of the organism's resistance natural cytotoxicity 


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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • P. F. Zabrodskii
    • 1
  1. 1.Department of ToxicologySaratov Medical UniversitySaratovUSSR

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