Abstract
It is determined that arterial hypertension induced by deoxycroticosterone results in the almost total disappearance of the nonactomyosin components of the thermomechanical responses of the thoracic section of the rat aorta wall. This may explain the known effect of the decreased mechanical stress generated by the vascular wall during hypertension. It is assumed that this decrease in the mechanical stress generated by nonactomyosin mechanisms is due to an increase in the conformational stability of collagen of the connective-tissue matrix.
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References
A. N. Shapovalov, M. F. Shuba, and V. I. Mirutenko,Dokl. Akad. Nauk SSSR,308, No 3, 748–752 (1989).
A. N. Shapovalov and M. F. Shuba,Fiziol. Zh., No 2, 57–63 (1994).
A. Arner, U. Malmgvist, and B. Uvelius,Acta Physiol. Scand.,124, 525–533 (1985).
F. V. Brozovich and K. G. Morgan,Amer. J. Physiol.,257, H1573-H1580 (1989).
Y. Dohi, K. Aoki, S. Fujimoto, M. Kojima, and T. Matsunda,J. Hypertens.,8, 261–267 (1990).
P. F. Dillon and R. A. Murphy,Circulat. Res.,50, 799–804 (1982).
C. Y. Kwan, L. Belbeck, and E. E. Daniel,Molec. Pharmacol,17, 137–140 (1980).
C. Y. Kwan, in:Calcium and Contractility. Smooth Muscle, Eds. A. K. Grover and E. E. Daniel, Clifton, USA (1985), pp. 299–325.
P. S. Mereland, R. C. Webb, and D. F. Bohr,Hypertension,4, Suppl., 99–107 (1982).
C. S. Packer and N. L. Stephens,Canad. J. Physiol. Pharmacol.,63, 669–674 (1985).
J. Pawlowski and K. Morgan,J. Physiol.,448, 121–132 (1992).
C. L. Seidel,Fed. Proc.,43, No 9, 2395–2398 (1984).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 1, pp. 33–36, January, 1995
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Shapovalov, A.N., Uzhvan, V.A., Filippov, I.B. et al. Nonactomyosin component of thermo-induced contractions of the vascular wall in hypertension. Bull Exp Biol Med 119, 28–31 (1995). https://doi.org/10.1007/BF02445922
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DOI: https://doi.org/10.1007/BF02445922