Bulletin of Experimental Biology and Medicine

, Volume 119, Issue 4, pp 389–392 | Cite as

Role of various murine B-lymphocyte subpopulations in the immune response to T-independent antigens

  • N. N. Logunova
  • I. N. Chernyshova
  • E. V. Sidorova
Microbiology and Immunology


Polyclonal antibodies to Lyb 5+ antigen of murine B lymphocytes are obtained and a methodological approach to the detection of cells carrying this antigen is developed with the aim of investigating the role of various subpopulations of mouse B lymphocytes in polyclonal activation induced by T-independent type 2 antigen. Hybridomas producing anti-Lyb 5.1 antibodies are obtained.

Key Words

B lymphocytes surface antigens antibodies to Lyb 5 antigen 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • N. N. Logunova
    • 1
  • I. N. Chernyshova
    • 1
  • E. V. Sidorova
    • 1
  1. 1.Department of Immunoglobulin Biosynthesis, Research Institute of Viral PreparationsRussian Academy of Medical SciencesMoscow

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