Bulletin of Experimental Biology and Medicine

, Volume 119, Issue 4, pp 356–358 | Cite as

Spectrum of histone proteins and acridine orange binding by liver cell chromatin in rats at different times after partial hepatectomy

  • L. E. Panin
  • I. G. Svechnikova
  • N. N. Mayanskaya
Biophysics and Biochemistry


Changes in the spectrum of hepatic histones characteristic of active chromatin were observed in rats as early as 3 h after partial hepatectomy. At 6–9 h postsurgery, acridine orange binding to deproteinized chromatin areas was considerably increased. At 13 h the histone spectrum of liver cells from operated rats did not differ from that of control samples from sham-operated animals.

Key Words

partial hepatectomy histones chromatin activation rat liver 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • L. E. Panin
    • 1
  • I. G. Svechnikova
    • 1
  • N. N. Mayanskaya
    • 1
  1. 1.Institute of Biochemistry, Siberian Division of the RussianAcademy of Medical SciencesNovosibirsk

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