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Role of mast cells in reparative processes in inflammation

  • Pathological Physiology and General Pathology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Using the model of acute infectious peritonitis in rats, it is shown that inflammation induced in the absence of mast cells is characterized by marked inhibition of reparative processes. The most significant accumulation of functionally active fibroblasts and the development of granulations and young connective tissue in the mesentery occur 5–10 days after flogogen injection in the natural development of inflammation and after 10–20 days in the absence of mast cells. The data suggest that under natural conditions mast cells directly or indirectly stimulate reparative processes.

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Authors and Affiliations

  1. Department of Pathological Physiology, Kharkhov Medical Institute, Kharkov, USSR

    N. A. Klimenko & S. V. Tatarko

Authors
  1. N. A. Klimenko
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  2. S. V. Tatarko
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 3, pp. 262–265, March, 1995

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Klimenko, N.A., Tatarko, S.V. Role of mast cells in reparative processes in inflammation. Bull Exp Biol Med 119, 252–255 (1995). https://doi.org/10.1007/BF02445828

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  • DOI: https://doi.org/10.1007/BF02445828

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