Bulletin of Experimental Biology and Medicine

, Volume 118, Issue 3, pp 993–995 | Cite as

Significance of bacterial agglutination in the development of experimental sepsis

  • A. A. Pal'tsyn
  • E. G. Kolokol'chikova
  • I. A. Grishina
  • N. V. Chervonskaya
  • A. K. Badikova
  • E. P. Popova
Microbiology and Immunology
  • 24 Downloads

Abstract

The development of signs of generalized infection were studied in rats infected with a suspension ofPseudomonas aeruginosa, with dissociated (controls) or agglutinated (experiment) immune serum. All signs of the generalization of the process were reliably lower in the experiment than in the control. A favorable course of the infection after the administration of agglutinated agent indicated that the infection was generalized and secondary foci were initiated during the first days postinoculation, when antibodies to the agent had not yet been produced.

Key Words

antibodies agglutination bacteremia sepsis 

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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • A. A. Pal'tsyn
    • 1
  • E. G. Kolokol'chikova
    • 1
  • I. A. Grishina
    • 1
  • N. V. Chervonskaya
    • 1
  • A. K. Badikova
    • 1
  • E. P. Popova
    • 1
  1. 1.Pathoanatomy Department, Laboratory for the Prevention and Treatment of Bacterial Infections, A. V. Vishnevskii Institute of SurgeryRussian Academy of Medical SciencesMoscow

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