Bulletin of Experimental Biology and Medicine

, Volume 118, Issue 3, pp 929–932 | Cite as

The sympathetic nervous system is not involved in the development of atropine tachycardia

  • V. M. Smirnov


There is a consensus that the vagus nerve produces a permanent (tonic) inhibitory effect on heart activity. However, some recent experimental findings attest that the vagus tone is not pronounced and suggest that excittion of the sympathico-adrenal system is the cause of atropine tachycardia. We found in acute and chronic experiments that the blockage of the sympathetic nervous system does not abolish atropine- and methacin-induced tachycardia. At rest heart activity is regulated by the vagus as well as by humoral agents circulating in the blood.

Key Words

heart regulation sympathetic nervous system 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • V. M. Smirnov
    • 1
  1. 1.Department of PhysiologyRussian State Medical UniversityMoscow

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