Skip to main content
SpringerLink
Log in

Effect of semax heptapeptide on the human electroencephalogram

  • Experimental Methods for Clinical Practice
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of the new regulatory peptide Semax (ACTH4–10 fragment) on the electroencephalogram of a healthy person was studied. Semax was administered at 0.5 mg/kg intranasally in 9 volunteers without causing any nervous system pathology. The control group comprised 6 examinees treated in the same way with distilled water. The effect of Semax manifested itself on the electroencephalogram as a boost of biopotential strength in all ranges but especially in that of the α-rhythm, the zonal differences of which were enhanced, without any pathological signs being evident.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. L. R. Zenkov and M. A. Ronkin, in:Functional Diagnosis of Nervous Diseases [in Russian], Moscow (1991), pp. 7–146.

  2. M. A. Ponomareva-Stepnaya, V. N. Nezavibat'ko, L. V. Antonova,et al., Khim.-Farm. Zh., No 7, 790–795 (1984).

    Google Scholar 

  3. D. De Wied, in:Frontiers in Neuroendocrinology, Oxford (1969), pp. 97–140.

Download references

Author information

Authors and Affiliations

  1. Research Institute of Traditional Therapeutic Methods, Ministry of Health and the Medical Industry of Russia, Moscow

    M. V. Koroleva, E. E. Meizerov, V. N. Nezavibat'ko, A. A. Kamenskii & V. A. Dubynin

  2. Institute of Molecular Genetics, Russian Academy of Sciences, Moscow

    M. V. Koroleva, E. E. Meizerov, V. N. Nezavibat'ko, A. A. Kamenskii & V. A. Dubynin

  3. Department of Human and Animal Physiology, Biology Faculty, Moscow State University, Moscow, USSR

    M. V. Koroleva, E. E. Meizerov, V. N. Nezavibat'ko, A. A. Kamenskii & V. A. Dubynin

Authors
  1. M. V. Koroleva
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. E. Meizerov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. N. Nezavibat'ko
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. A. Kamenskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. A. Dubynin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No 1, pp. 116–117, January, 1996

Rights and permissions

Reprints and permissions

About this article

Cite this article

Koroleva, M.V., Meizerov, E.E., Nezavibat'ko, V.N. et al. Effect of semax heptapeptide on the human electroencephalogram. Bull Exp Biol Med 121, 108–109 (1996). https://doi.org/10.1007/BF02445721

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02445721

Key Words

Search

Navigation