Comparative study of metastases of human melanoma strain Mel-7 in nude and beige/nude mice
- 17 Downloads
Metastases to the lungs after subcutaneous transplantation of human melanoma Mel-7 to nude and beige/nude mice are situated deep inside the organ closer to the root. Despite a larger size of xenograft in nude mice, the metastasizing process was more expressed in beige/nude mice with a more severe immunodeficiency, which was reflected in an increased number of metastases and their greater total volume in the lungs.
Key Wordsmetastases xenograft nude mice
- 5.E. S. Revasova, Y. N. Solovjov, P. M. Chumakov,et al., in:Immunodeficient Mice in Oncology, Eds. H. H. Fiebiget al., Basel (1992), pp. 126–127.Google Scholar