Abstract
Pathological changes in internal organs are seen in some offspring of intact females and males treated with platidiam 1 month before mating. One case of malformation was found in the progeny of cytostatic-treated females. High embryonal mortality is noted in animals treated with cytostatics 3 and 6 months before mating. Delayed ossification is observed in some animals of almost all experiments groups.
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References
M. M. Belen'kii, in:Quantifying Pharmacological Effects [in Russian], Leningrad (1963), pp. 81–106.
V. A. Gorbunova,Vopr. Onkol., No. 3, 325–330 (1989).
A. P. Dyban, V. S. Baranov, and I. M. Akimova,Arkh. Anat.,59, No. 10, 89–100 (1970).
M. A. Presnov, L. A. Konovalov, and V. P. Korol'chuk,Vestn. Akad. Med. Nauk SSSR, 68–80 (1979).
M. Barbosa Maria Baki, S. Gungu, and J. Badrogi,Acta Paediatr. Hung.,32, No. 1, 11–30 (1992).
A. Genetika, R. Miro, and M. R. Cabollin,Hum. Reprod.,5, No. 3, 286–290 (1990).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 11, pp. 516–519, November, 1997