Circadian and seasonal variations in blood lymphocyte dehydrogenase activities in women with secondary immunodeficiency and acute nonspecific gynecological inflammations

  • A. V. Shurlygina
  • G. I. Litvinenko
  • T. I. Dergacheva
  • V. A. Trufakin
Experimental Biology


Development of secondary immunodeficiency in patients with acute nonspecific inflammatory diseases of the uterine appendages is associated with disorders in chronobiological characteristics of energy metabolism in blood lymphocytes. The differences in the enzyme activities in patients and donors are observed in the evening during all seasons of the year; seasonal variations are typical only of the morning enzyme spectrum.

Key Words

dehydrogenases lymphocyte biorhythms gynecological inflammations 


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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • A. V. Shurlygina
    • 1
  • G. I. Litvinenko
    • 1
  • T. I. Dergacheva
    • 1
  • V. A. Trufakin
    • 1
  1. 1.Institute of Clinical and Experimental LymphologySiberian Division of the Russian Academy of Medical SciencesNovosibirsk

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